For Canadian residents only


Synvisc-One (hylan G-F 20) is a viscosupplement injection for osteoarthritis of the knee. Made from a natural substance that lubricates and cushions your joint, Synvisc-One can provide knee pain relief and improved mobility over 6 months with just one simple injection.

Learn how to make Synvisc-One part of your osteoarthritis treatment plan

What’s in a joint?

A healthy joint has cartilage and synovial fluid that protect and cushion the bones.

If you are living with osteoarthritis, the cartilage in your joint has worn down and the synovial fluid is no longer able to cushion your joint. When this happens, your bones rub against each other, causing pain, joint stiffness and swelling.

When you get an injection of Synvisc-One, you replace the damaged synovial fluid in your knee with a natural substance that protects, cushions and lubricates the joints.

Le cartilage s’effrite, Des excroissances osseuses peuvent se former, Le liquide synovial s’épanche
  • ACartilage wears away
  • BBone spurs may develop
  • CJoint fluid breaks down

In knees with osteoarthritis, the joint fluid (called synovial fluid) can break down. When this happens your knees no longer have the cushioning and lubrication that they need.

Synvisc-One remplace le liquide synovial
  • DSynvisc-One replaces joint fluid

Synvisc-One replaces the worn out synovial fluid to relieve the pain and improve the knee joint’s ability to act as a natural shock absorber.

Mother nature knows best.

Synvisc-One mimics healthy young synovial fluid to protect your knee joint.

Healthy young synovial fluid offers the ideal balance of cushioning and lubrication to protect your joints.

Synvisc-One (hylan G-F 20) mimics these superior qualities and hylan-G-F 20 has been shown to provide significant pain relief from osteoarthritis over a long period of time.

SYNVISC/Synvisc-One (hylan G-F 20)

SYNVISC/Synvisc-One (hylan G-F 20)

Low molecular weight viscosupplements

Low molecular weight viscosupplements

What about your other joints?

other joints

In addition to Synvisc-One for the knee, hylan G-F 20 is also available simply as SYNVISC® to treat the pain and discomfort of osteoarthritis in the hip, shoulder and ankle.

Talk to your doctor about SYNVISC and Synvisc-One to see which is the right choice for you!

hylan G-F 20

SYNVISC goes to work right where the pain begins without the need for surgery!

  • Lubricates and cushions your joint
  • Decreases pain and discomfort
  • Helps you get back to your daily activities
  • Helps protect your cartilage against further damage
  • Approved for use multiple times
  • Could delay the need for total knee replacement surgery